Emizimbeni yabantu,i-collagenibaluleke njengenhliziyo emizimbeni yethu.Kusisiza ukuthi sihlale sibasha futhi sinempilo.Lapho sizalwa, i-collagen isezingeni eliphezulu, kodwa njengoba sikhula, ukuntuleka kwe-collagen kwenzeka, futhi siyakhula.Kodwa-ke, ukuguga kungancishiswa ngokuthatha izithako ze-collagen.Kodwa inkinga lapha ukuthi kunezinhlobo ezingama-28 ze-Collagen emizimbeni yethu, futhi kubaluleke kakhulu ukuqonda ukuthi yiluphi uhlobo lwe-Collagen olwenza ukuthi singasebenzisi ngokweqile kolunye uhlobo.Ngakho-ke, qhubeka uzigcine usemusha futhi unempilo.
Umfanekiso-no-1-Izinhlobo-ze-Collagen
➔ Uhlu lokuhlola
1.Iyini i-Collagen?
2.Isebenza Kanjani I-Collagen Emzimbeni?
3.Izinhlobonhlobo ze-Collagen: Yiziphi Izinhlobo Ezihlukene?
Njengoba nje izinwele zethu zikhula ngokwemvelo, i-Collagen iyiphrotheni eyenziwa umzimba wethu njalo.
Umfanekiso ongu-2-what-is-collagen
Kuyamangaza ukuqaphela ukuthi emzimbeni womuntu, cishe i-30% yesilinganiso samaprotheni siphethwe yi-Collagen, futhi uma kuqhathaniswa nesisindo somzimba wonke, amaprotheni akha i-14 ~ 16%.I-Collagen ikhona yonke indawo, njengomoya eMhlabeni;isibonelo, ungayithola ezithweni, emathunjini, emathanjeni, esikhunjeni, nakuzo zonke ezinye izingxenye zomzimba womuntu.
2) I-Collagen yenzani emzimbeni?
Lokhu okulandelayo yizindima ze-Collagen emzimbeni wethu:
Umfanekiso we-3 Iyini indima ye-collagen emzimbeni.
✓Ngaphakathi kwesikhumba -igcina ithambile, inwebeka, iqinile, futhi ingenamibimbi.
✓Ungqimba olungaphezulu ezithweni namathumbu - sebenza njengesendlalelo esivikelayo
✓Ngaphakathi emathanjeni - isiza ekwakhiweni kwamathambo, kwandisa ukuminyana, futhi yehlise ukukhumuzeka kwamathambo
✓Kumajoyinti - isiza ekwakhekeni kwazo lapho zisebenza njengamaphoyinti okunamathiselwe & izinto ezimunca ukushaqeka
✓Izinzipho -I-Collagen yakha i-keratin, eyenza izinzipho.Ngakho-ke, i-Collagen inesibopho sokukhula kwezinzipho kanye nempilo
✓Izinwele -Iphrotheni eyinhloko, i-keratin, esezinweleni, ivela ku-amino acid ethile ye-Collagen, ngakho ngokuyisisekelo, i-Collagen yenza izinwele.Ngaphezu kwalokho, isendlalelo se-dermis, lapho izimpande zezinwele (izimpande) zikhona, zenziwe kakhulu nge-Collagen.
✓Imithambo yegazi -Imicu ye-collagen ikhona ngaphansi kongqimba lwangaphakathi lwemithambo yegazi ngendlela yenethiwekhi.Ngaphezu kwalokho, banikeza ukusekelwa kwesakhiwo, futhi ngesikhathi sokulimala, basebenza njengozibuthe wama-ejenti okwelapha futhi basize ukulungisa.
✓Phakathi kwemisipha yemisipha -isebenze njengengcina yemisipha, ihlale iboshelwe ndawonye futhi inikeze ukunwebeka kwezicubu.Ziphinde zisebenze njengendlela yokudlulisa amandla enkontileka ukusuka emisipha kuya kumathambo (amathambo, imisipha, imisipha).
3) Yiziphi izinhlobo ezahlukene ze-Collagen?
Umfanekiso ongu-4-Yiziphi-izinhlobo-ezihlukile-ze-Collagen
Ososayensi bathole izinhlobo ezingaphezu kuka-28 zeI-collagenfuthi ahlukaniswa ngokusekelwe ezintweni zawo zokwakha, ukuhlelwa kwesakhiwo, nemisebenzi abayenzayo.
Kulezi zinhlobo ezingama-28, kukhona ama-Collagens angu-5 anomphumela omningi, njengokuthi;
a) Uhlobo lwe-Collagen I(okuningi kakhulu)
b) Uhlobo lwe-Collagen II
c) Uhlobo lwe-Collagen III(okuningi kakhulu)
d) Uhlobo lwe-Collagen V
e) Uhlobo lwe-Collagen X
a) Thayipha I-Collagen & Ukusetshenziswa kwayo
“Uhlobo I-Collagen luyiprotheni ende, ene-triple-helical, futhi lwenziwe ngama-amino acid amathathu: i-glycine, i-proline, ne-hydroxyproline.Izinsalela ze-glycine zakha umnyombo we-triple helix, kuyilapho izinsalela ze-proline ne-hydroxyproline zinikeza ukuguquguquka namandla.”
Ungakwazi ukulinganisa ukubaluleka kwe-Type I Collagen kusukela endaweni yayo yokuqala esigabeni sokuqamba amagama ngoba iqukethe i-90% yawo wonke ama-Collagen emzimbeni womuntu, ikakhulukazi esikhumbeni, emathanjeni, nasezicubu ezixhumeneyo ( izintambo, imigqa, i-cartilage).
➔ Ukusetshenziswa Kohlobo I-Collagen
Njengoba Uhlobo I Collagen luningi esikhumbeni nasemathanjeni, ungalinganisa umsebenzi walo oyinhloko ukugcina isikhumba sisesisha nokugcina amandla amathambo - imininingwane enikezwe ngezansi;
✓Impilo yesikhumba:Uma unemibimbi, ukuxega, noma ukuhwalala esikhumbeni sakho, khona-ke inkinga yakho enkulu ukushoda kwe-Type I Collagen.
✓Ukufinyela kwemisipha: Thayipha I-Collagen nayo ibalulekile ekuvimbeni kwemisipha.Kuyasiza ukuxhuma imicu yemisipha futhi ivumela ukuthi ifinyeze futhi iphumule.
✓Ukwakheka kwemithambo yegazi:Uhlobo lwe-Collagen I nalo lubalulekile ekwakhekeni kwemithambo yegazi.Kuyasiza ukwakha izindonga zemithambo yegazi futhi igcine iqinile futhi inempilo.
✓Ukuphulukiswa kwesilonda:I-Collagen yohlobo I nayo ibalulekile ekwelapheni kwesilonda.Kuyasiza ukwenza utwayi phezu kwesilonda futhi kunikeza uhlaka lokukhula kwezicubu ezintsha.
✓Ukulungisa uqwanga:Amalunga omzimba womuntu enziwe ngento eyi-cushy ebizwa ngokuthi i-cartilage, futhi lolu qwanga lwenziwe ngokuyinhloko ngo-Type I Collagen.Uqwanga lusebenza njengento edonsa ukushaqeka kanye nephuzu elinciphisa ukungqubuzana phakathi kwamathambo amabili.
✓Ukwakheka kwamathambo:Ngaphandle kwamathambo, sifana nendwangu ende elele phansi.Umzimba wethu ukhiqiza amathambo ikakhulukazi ngo-Type I collagen.Ngakho-ke, i-Type I Collagen eyengeziwe isho ukukhiqizwa okungcono kwamathambo, ukuphulukiswa okusheshayo, nokwakheka kwamathambo okuqinile.
b) Uhlobo II I-Collagen Nokusetshenziswa kwayo
“Uhlobo II lwe-Collagen lwakhiwe amaketanga amathathu amade ama-amino acid ahlanganiswe ndawonye ukuze akhe i-triple helix.I-triple helix inikeza uhlobo lwe-II lwe-Collagen amandla nokuguquguquka. "
Ikhona ngobuningi ku-cartilage yelunga futhi inesibopho sokuletha ukuqina nokuguquguquka.Izithako ze-Collagen zohlobo lwe-II zivame ukwenziwa ngoqwanga lwenkukhu noma lwezinkomo.
➔ Ukusetshenziswa kohlobo lwe-II Collagen
✓Impilo ehlangene:I-Type II Collagen igcwele kakhulu ku-cartilage, ngakho kunengqondo ukuthi ukuthatha izithasiselo zayo kuzosiza ekwelapheni izifo zamathambo namalunga njenge-osteoarthritis, njll. Iphinde isize ukukhululeka ebuhlungwini bamalunga futhi yengeze ukuqina emalungeni ukuze anyakaze kangcono.
✓Impilo yesikhumba:Olunye ucwaningo lubonise ukuthi uhlobo lwe-II Collagen supplements lunganciphisa ukubukeka kwemibimbi namachashaza eminyaka futhi lusize ukuthuthukisa ukunwebeka kwesikhumba.
✓Impilo yamathumbu:Ezinye izifundo zocwaningo zibonise ukuthi uhlobo lwe-II lwezithako ze-Collagen lungasiza ukuvikela indawo yangaphakathi/yangaphandle yamathumbu kanye nokwenza ngcono ukugayeka kokudla kanye nokumuncwa kwemisoco.
✓Umsebenzi wesistimu yamasosha omzimba:Izithako ze-Collagen zohlobo lwe-II nazo ngezinye izikhathi zisetshenziselwa ukusiza amasosha omzimba ukulwa nezifo, okuholela ekululameni ngokushesha ezifweni.
c) Uhlobo III I-Collagen kanye Nokusetshenziswa kwayo
“Ngokwesakhiwo, Uhlobo IIII-collagenyakhiwe ngamaketanga e-alpha amathathu afanayo, okuyenza i-homotrimer, ngokungafani noHlobo I-Collagen, enamaketanga amabili e-alpha1 kanye neketango elilodwa le-alpha2.”
Uma kukhulunywa ngo-Type III collagen, iyisigaba sesi-2 esitholakala ngobuningi be-Collagen emzimbeni womuntu.Kusatshalaliswa kabanzi kuzo zonke izicubu ezihlukene ezifana namathumbu, imithambo yegazi, isibeletho, isikhumba, nezitho zomzimba.Ngokusho kwedatha evela ezingxenyeni ezihlukahlukene zomzimba womuntu, kuqoshwa isilinganiso sohlobo lwe-Collagen I kuya ku-Type III ye-Collagen sifana no-4:1 ( isikhumba ), 3:1 ( izitho), njll.
Lolu hlobo lwe-Collagen, olubizwa ngokuthi i-fibrillar, ludala imicu emide, emincane enikeza izicubu amandla nokuguquguquka.Ngaphezu kwalokho, iphinde isize izilonda ziphole ngokushesha.Ukwengeza, igcina ukwakheka kwemithambo yegazi nezinye izitho, kusize ukusebenza kwazo ngendlela efanele.
➔ Ukusetshenziswa kohlobo lwe-II Collagen
✓Impilo ehlangene:I-Collagen yohlobo lwe-III ayiyona into eningi emathanjeni naku-cartilage, kodwa ikhona futhi isiza ukusekela ezinye izinhlobo ze-cartilage ukugcina amandla nempilo yamathambo.
✓Impilo yesikhumba:I-Collagen yohlobo lwe-III igcwele kakhulu esikhumbeni, njenge-Type I Collagen, futhi isiza isikhumba ukuthi sigweme imigqa emihle, kamuva ephenduka imibimbi.Ngaphezu kwalokho, i-Type III Collagen yakha inethiwekhi yesakhiwo ngaphansi kwesikhumba ukuze igcine isikhumba siqinile, kodwa njengoba i-Collagen inwebeka, isikhumba sihlala sinwebeka.
✓Impilo yezinwele: I-Tpye III Collagen ihlinzeka ngezinto ezingavuthiwe zokwakheka kwezinwele, ngakho-ke ithuthukisa ukukhula kwezinwele namandla.Ngaphezu kwalokho, amaprotheni ohlobo lwe-III nawo atholakala esikhunjeni lapho izimpande zezinwele zikhona.Ngamafuphi, ukuthatha izithasiselo ze-Collagen zohlobo lwe-III kuzosiza umuntu onezinwele ezibuthakathaka.
✓Ukuphulukiswa kwesilonda:Uhlobo lwe-III luyiprotheyini ye-Collagen yesibili egcwele kakhulu emisipha nezitho, futhi njengoba wazi, i-Collagen iwuzibuthe wemvelo wokuphulukisa amaseli;uma kwenzeka noma yikuphi ukulimala, i-Collagen isiza ukwakha izicubu ezintsha ngokushesha.
✓Ukuzivikela:I-Collagen yohlobo lwe-III ingasiza ekuthuthukiseni ukuzivikela komzimba ngokuvusa ukukhiqizwa kwamangqamuzana egazi amhlophe.Imvamisa isetshenziselwa izithasiselo zokwelapha izifo ze-autoimmune nezinye izifo zamasosha omzimba.
d) Thayipha i-Collagen ye-V kanye nokusetshenziswa kwayo
“Lolu hlobo lwe-Collagen luhlukaniswa njenge-fibrillar, luhlanganisa imicu emide, efana nekhebula enikeza amandla nokuvumelana nezimo ezicutshini - lusebenza ne-Type I kanye ne-Type III Collagens, idale isikafula sezicubu nezitho zomzimba.”
I-Collagen yohlobo lwe-V ayiningi njengezinye izinhlobo ezinhlanu ezinkulu ze-Collagen, kodwa yenza imisebenzi ebalulekile njengokwenza i-cornea yamehlo, izingqimba zesikhumba nezinwele, kanye nezicubu ze-placenta.Isebenza ngaphakathi kwe-matrix engaphandle kwezicubu ezihlukahlukene, njengesikhumba, amathambo, imithambo yegazi kanye ne-placenta, inikeza ukusekelwa okubalulekile kwesakhiwo.
➔ Ukusetshenziswa kohlobo lwe-II Collagen
✓Izinwele nezinzipho:Isekela impilo kanye nokuqina kwezinwele nezinzipho.
✓Impilo Yamehlo:Iyingxenye ebalulekile ye-cornea, efaka isandla ekugcineni isimo seso nokucaca.
✓Ukuqina Kwesikhumba:I-Collagen yohlobo lwe-V isiza ekusimamiseni impilo yesikhumba, inikele emandleni nasekunwebekeni kwayo.
✓Imithambo yegazi: I-Collagen yohlobo lwe-V yakha ukwakheka kwezindonga zemithambo yegazi, okunomthelela ekuzinzeni kwazo nokusebenza okufanele.
✓Ukwakhiwa Kwezicubu: I-collagen yohlobo lwe-V isiza ezinye izinhlobo ze-collagen ekukhiqizeni izicubu ezihlukahlukene nezendlalelo zesitho, ngakho isiza ekukhuleni kwazo okunempilo.
e) Thayipha X Collagen & Ukusetshenziswa kwayo
"Uhlobo lwe-X Collagen luhlanganisa i-helix emfushane kathathu ye-Collagen ezungezwe izizinda ezimbili ezingezona i-collagenous, i-NC2 ne-NC1."
Isiza ekubopheni amaminerali abalulekile, njenge-calcium, emiculweni ye-Collagen, ithuthukisa amandla amathambo - ngokwenza kanjalo, inomthelela ekuqineni kwesistimu yethu yamathambo.
Ngokungafani nezinye izinhlobo ze-Collagen, ayidali imicu emide kodwa yakha inethiwekhi yemicu emifushane.Le nethiwekhi ehlukile inikeza amandla kanye nokuguquguquka kwepuleti lokukhula kanye nendawo ebaliwe ye-articular cartilage.
➔ Ukusetshenziswa kohlobo lwe-II Collagen
Okulandelayo okunye ukusetshenziswa kohlobo X Collagen;
✓Iqhaza Elikhethekile:Noma itholakala ngamanani amancane, ukusebenza kwayo okuhlukile ekuthuthukisweni kwamathambo kugqamisa ukubaluleka kwayo.
✓Isibonisi Soshintsho:I-Type X Collagen isebenza njengomaka phakathi nokuthuthukiswa kwamathambo, okubonisa ukusuka ku-cartilage kuya ethanjeni eliqinile.
✓I-Growth Plate Inkomba:Ukuba khona kwayo emapuletini okukhula kubonisa uguquko olubalulekile olusekela ukukhula kwamathambo amade.
✓Umsizi Wokukhula:Ngokusiza lolu shintsho, Uhlobo lwe-X Collagen luqinisekisa ukuthi amathambo akhula kokubili ngobude namandla, okubalulekile empilweni eqinile yamathambo nobuqotho besakhiwo.
➔ Isiphetho
Abakhiqizi be-collagenemhlabeni jikelele yenza izithasiselo ezikhethekile ezigxile ekukhiqizeni uhlobo oluthile lwe-Collagen, njengoHlobo I noma Uhlobo II nezinye.Nokho, kubalulekile ukuqaphela ukuthi abanye banjalobovine Collagen abakhiqizi, ezinye ziyingulube, kanti ezinye zisebenzisa izingxenye zezilwane ezixubile - okungaba inkinga ngekhwalithi nakwamanye amasiko ( ingulube i-Collagen i-haram in Islam).
Kodwa-ke, thina kwa-Yasin sihlose ukwenza i-Collagen kuzo zonke izinhlobo zezilwane kodwa ezitsheni ezithile ukuqinisekisa ukuthi abathengi bathola lokho abakufunayo.Ngakho-ke, uma ungowabahlinzeki bamaprotheni noma abahlinzeki bempushana ye-Collagen, singaqinisekisa ukuthi uthola imikhiqizo eyi-100% evela kithi.
Isikhathi sokuthumela: Sep-08-2023